Egg and milk allergy in adults
Egg and milk allergy in adults
复制标题
成人鸡蛋和牛奶过敏
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
C. Bindslev‐Jensen
中科院分区：
文献类型：
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作者：
A. Norgaard;C. Bindslev‐Jensen
Nineteen adult patients representing a total of 24 medical histories of immediate adverse reactions to egg or cows’ milk underwent 1) standardized questioning about signs/symptoms occurring less than 2 h after ingestion of egg or milk, 2) skin prick test, RAST and histamine release test, and 3) titrated, oral, double‐blind, placebo‐controlled challenge (DBPCFC) with fresh egg or milk. Eleven medical histories (46%) were confirmed by DBPCFC in 10 patients (53%). All DBPCFC‐positive patients experienced gastrointestinal symptoms, and in 80% of the patients, gastrointestinal symptoms were accompanied by respiratory or skin symptoms. Threshold doses varied between 50 mg and 250 g, with 4 patients presenting objective signs following 5 g or less. DBPCFC‐positive patients reported significantly more symptoms and had a significantly higher number of positive tests than had DBPCFC‐negative patients. None of the tests were in significant concordance with DBPCFC, although RAST showed a sensitivity of 100%. Thus, DBPCFC cannot be substituted in the diagnosis of milk and egg allergy in adults. The use of titrated, fresh foods in DBPCFC proved to be a safe and well‐controlled procedure.
免疫介导的食物过敏：食物挑战程序的重要性。
DOI：
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发表时间：
1988
期刊：
Annals of allergy
影响因子：
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作者：
Sampson,HA
通讯作者：
Sampson,HA
影响因子：
14.2
作者：
DAUL, CB;MORGAN, JE;LEHRER, SB
通讯作者：
LEHRER, SB
IgE 介导的食物不耐受。
DOI：
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发表时间：
1988
期刊：
The Journal of allergy and clinical immunology
影响因子：
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作者：
Sampson,HA
通讯作者：
Sampson,HA