Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis.
Standardization of the modified Rodnan skin score for use in clinical trials of systemic sclerosis.
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DOI：
10.5301/jsrd.5000231
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发表时间：
2017-01
影响因子：
2
通讯作者：
Denton CP
中科院分区：
文献类型：
--
作者：
Khanna D;Furst DE;Clements PJ;Allanore Y;Baron M;Czirjak L;Distler O;Foeldvari I;Kuwana M;Matucci-Cerinic M;Mayes M;Medsger T Jr;Merkel PA;Pope JE;Seibold JR;Steen V;Stevens W;Denton CP
改良罗德曼皮肤评分（mRSS）是一种测量皮肤厚度的方法，在系统性硬化症（硬皮病）的临床试验中用作主要或次要结局指标。这篇最新的综述提供了mRSS发展的历史视角，总结了mRSS作为结果测量的表现，提供了评估mRSS的指导，并提出了将mRSS纳入临床试验的建议。
The modified Rodnan skin score (mRSS) is a measure of skin thickness and is used as a primary or secondary outcome measure in clinical trials of systemic sclerosis (scleroderma). This state-of-art review provides a historical perspective of the development of the mRSS, summarizes the performance of mRSS as an outcome measure, provides guidance on assessing mRSS, and makes recommendations for incorporation of the mRSS into clinical trials.