Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment.
Microfluidic Pneumatic Cages: A Novel Approach for In-chip Crystal Trapping, Manipulation and Controlled Chemical Treatment.
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DOI：
10.3791/54193
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发表时间：
2016-07-12
期刊：
影响因子：
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通讯作者：
Puigmartí-Luis J
中科院分区：
文献类型：
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作者：
Abrishamkar A;Paradinas M;Bailo E;Rodriguez-Trujillo R;Pfattner R;Rossi RM;Ocal C;deMello AJ;Amabilino DB;Puigmartí-Luis J
表面结构的精确定位和受控化学处理是普通实验室技术面临的重大挑战。在这里，我们介绍了一种基于微流控技术的技术，它采用双层微流控器件，可以在微流控通道表面捕获和定位原位和非原位合成的结构。至关重要的是，我们展示了如何使用这种设备对芯片上捕获的结构进行受控化学反应，并展示了如何使用这种技术精确地修改晶体分子材料的合成路径及其在微流控通道中的位置。这种方法为表面结构的受控组装及其后续处理提供了新的机会。
The precise localization and controlled chemical treatment of structures on a surface are significant challenges for common laboratory technologies. Herein, we introduce a microfluidic-based technology, employing a double-layer microfluidic device, which can trap and localize in situ and ex situ synthesized structures on microfluidic channel surfaces. Crucially, we show how such a device can be used to conduct controlled chemical reactions onto on-chip trapped structures and we demonstrate how the synthetic pathway of a crystalline molecular material and its positioning inside a microfluidic channel can be precisely modified with this technology. This approach provides new opportunities for the controlled assembly of structures on surface and for their subsequent treatment.