Genetic variants affecting meat and milk production traits appear to have effects on reproduction traits in cattle
Genetic variants affecting meat and milk production traits appear to have effects on reproduction traits in cattle
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DOI：
10.1111/j.1365-2052.2011.02272.x
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发表时间：
2012-08-01
期刊：
影响因子：
2.4
通讯作者：
Hawken, R.
中科院分区：
文献类型：
--
作者：
Collis, E.;Fortes, M. R. S.;Hawken, R.
位于基因ABCG 2、DGAT 1、LEP、PRLR、RORC、CAPN 1和CAST中的多态性先前已与产奶或产肉性状相关。在这项研究中，研究了这些多态性对生殖性状[青春期年龄（AGECL）、产后乏情期间隔（PPAI）和断奶前排卵能力（PW）]以及一组相关性状（如体重、生长和胰岛素样生长因子I血清浓度）的显著影响。在两个样本的热带适应肉牛：婆罗门（N = 932）和热带复合（N = 1097）的多态性的影响进行了检查。DGAT 1基因的一个多态性与青春期年龄相关（P = 0.042），CAPN 1基因的两个多态性与PPAI（P = 0.033）和排卵能力相关（P = 0.017）。繁殖性状的有利等位基因不一定是生产性状的有利等位基因。与它们最初被发现的特征相比，这些多态性对生殖特征的影响很小。
Polymorphisms located in the genes ABCG2, DGAT1, LEP, PRLR, RORC, CAPN1 and CAST previously have been associated with milk or meat production traits. In this study, these polymorphisms were examined for significant effects on reproductive traits [age at puberty (AGECL), post-partum anoestrus interval (PPAI) and the ability ovulate prior to weaning (PW)] and on a panel of correlated traits such as weight, growth and serum concentration of insulin-like growth factor I. The effects of the polymorphisms were examined in two samples of tropically adapted beef cattle: Brahman (N = 932) and Tropical Composites (N = 1097). A polymorphism in the gene DGAT1 was associated with age at puberty in the combined sample (P = 0.042), and two polymorphisms in CAPN1 were associated with PPAI (P = 0.033) and with the ability ovulate PW (P = 0.017). The favourable allele for reproductive traits was not always the favourable allele associated with production traits. The effects of these polymorphisms on reproductive traits were small compared to their effects on the traits for which they were originally discovered.