First detection of G12 rotaviruses in newborns with neonatal rotavirus infection at all India institute of medical sciences, New Delhi, India
First detection of G12 rotaviruses in newborns with neonatal rotavirus infection at all India institute of medical sciences, New Delhi, India
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DOI：
10.1128/jcm.01288-07
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发表时间：
2007-11-01
影响因子：
9.4
通讯作者：
Bhan, A. K.
中科院分区：
文献类型：
--
作者：
Ray, Pratima;Sharma, S.;Bhan, A. K.
2005年至2006年期间，在全印度医学科学研究所的托儿所首次在无症状轮状病毒感染的新生儿中检测到轮状病毒基因型G12株（从受感染婴儿中分离出的39株轮状病毒株中有74%为基因型G12）。这些新生菌株的VP7基因序列分析显示，与世界各地报道的其他G12菌株高度同源，表明这些菌株是最近在人类中出现的。新生儿的这种医院感染是将新型轮状病毒血清型引入社区的潜在来源。
Rotavirus genotype G12 strains were detected for the first time among newborns with asymptomatic rotavirus infection (74% of 39 rotavirus strains isolated from the infected infants were genotype G12) in the nursery of the All India Institute of Medical Sciences during a period from 2005 to 2006. Sequence analysis of the VP7 genes from these neonatal strains indicated a high level of homology to other G12 strains reported worldwide, suggesting the recent emergence of these strains in humans. Such nosocomial infections of newborns represent a potential source of introduction of novel rotavirus serotypes into the community.