Using family history information to promote healthy lifestyles and prevent diseases; a discussion of the evidence
Using family history information to promote healthy lifestyles and prevent diseases; a discussion of the evidence
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DOI：
10.1186/1471-2458-10-248
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发表时间：
2010-05-13
影响因子：
4.5
通讯作者：
Timmermans, Danielle R. M.
中科院分区：
文献类型：
--
作者：
Claassen, Liesbeth;Henneman, Lidewij;Timmermans, Danielle R. M.
背景资料：家族史反映了遗传易感性以及共同的环境和行为因素，是常见慢性多因素疾病（如心血管疾病、2型糖尿病和许多癌症）的重要风险因素。讨论：本文的目的是讨论使用家族史作为常见慢性病一级预防工具的证据，特别是为促进健康的生活方式采取有针对性的干预措施。以下问题得到解决：（1）作为个人疾病风险的决定因素，家族史信息的价值是什么？(2)如何利用家族史信息来激励高危个体采取和保持健康的生活方式以预防疾病？和（3）需要哪些额外的研究来评估家族史信息作为促进健康生活方式的工具的潜在价值？总结：除了风险评估，家族史信息还可用于个性化健康信息，这可能比标准化健康信息更有效地促进健康生活方式。需要对这种工具的有效性进行更多的研究。
Background: A family history, reflecting genetic susceptibility as well as shared environmental and behavioral factors, is an important risk factor for common chronic multifactorial diseases such as cardiovascular diseases, type 2 diabetes and many cancers.Discussion: The purpose of the present paper is to discuss the evidence for the use of family history as a tool for primary prevention of common chronic diseases, in particular for tailored interventions aimed at promoting healthy lifestyles. The following questions are addressed: (1) What is the value of family history information as a determinant of personal disease risk?; (2) How can family history information be used to motivate at-risk individuals to adopt and maintain healthy lifestyles in order to prevent disease?; and (3) What additional studies are needed to assess the potential value of family history information as a tool to promote a healthy lifestyle?Summary: In addition to risk assessment, family history information can be used to personalize health messages, which are potentially more effective in promoting healthy lifestyles than standardized health messages. More research is needed on the evidence for the effectiveness of such a tool.