A novel chiral separation material: polymerized organogel formed by chiral gelators for the separation of D- and L-phenylalanine
A novel chiral separation material: polymerized organogel formed by chiral gelators for the separation of D- and L-phenylalanine
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DOI：
10.1002/jmr.831
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发表时间：
2007-07-01
影响因子：
2.7
通讯作者：
Yang, Yajiang
中科院分区：
文献类型：
--
作者：
Fu, Xinjian;Yang, Yang;Yang, Yajiang
合成了手性化合物N-硬脂酰-N '-硬脂酰-L-苯丙氨酸，并将其用作可聚合溶剂（如甲基丙烯酸羟乙酯（HEMA）、苯乙烯等）的凝胶化剂。凝胶化剂聚集体的扫描电镜（SEM）图像显示为纤维状螺旋，是典型的手性聚集体，直径为100-200 nm。溶剂分子通过毛细管力固定在有机凝胶的三维网络结构中。随后，通过原位UV照射聚合含交联剂聚乙二醇二甲基丙烯酸酯（PEG 200 DMA）的HEMA有机凝胶。通过乙醇萃取去除凝胶因子聚集体后，得到多孔聚合有机凝胶。利用聚合有机凝胶对D-和L-苯丙氨酸进行了手性分离。结果表明，聚合有机凝胶对L-苯丙氨酸的吸附效率与凝胶剂和交联剂的浓度有关。版权所有（C）2007约翰威利父子有限公司
N-Stearine-N'-stearyl-L-phenylalanine, a chiral compound, was synthesized and used as a gelator for the gelation of polymerizable solvents, such as beta-hydroxyethyl methacrylate (HEMA), styrene, etc. The scanning electron microscope (SEM) images of the gelator aggregates show fibril-like helices, typical chiral aggregates with diameters of 100-200 nm. The solvent molecules were immobilized by capillary forces in the three-dimensional network structures of the organogels. The HEMA organogels containing crosslinker polyethylene glycol dimethacrylates (PEG200DMA) were subsequently polymerized by in situ UV irradiation. A porous polymerized organogels were obtained after removal of gelator aggregates through ethanol extraction. The chiral separation of D- and L-phenylalanine was carried out by the adsorption of the polymerized organogels. The adsorption efficiency of L-phenylalanine on the polymerized organogels was found to be dependent on the concentration of the gelator and crosslinker. Copyright (C) 2007 John Wiley & Sons, Ltd.