THE PREPARATION AND PROPERTIES OF NOVEL REVERSIBLE POLYMER-PROTEIN CONJUGATES - 2-OMEGA-METHOXYPOLYETHYLENE (5000) GLYCOXYMETHYLENE-3-METHYLMALEYL CONJUGATES OF PLASMINOGEN ACTIVATORS
THE PREPARATION AND PROPERTIES OF NOVEL REVERSIBLE POLYMER-PROTEIN CONJUGATES - 2-OMEGA-METHOXYPOLYETHYLENE (5000) GLYCOXYMETHYLENE-3-METHYLMALEYL CONJUGATES OF PLASMINOGEN ACTIVATORS
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DOI：
10.1016/0014-5793(87)80319-8
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发表时间：
1987-11-02
期刊：
影响因子：
3.5
通讯作者：
KALINDJIAN, SB
中科院分区：
文献类型：
--
作者：
GARMAN, AJ;KALINDJIAN, SB
The preparation of a reagent capable of reversibly attaching polyethylene glycol to proteins and the use of this material in modifying the plasminogen activators urokinase‐ and tissue‐type plasminogen activator are described. The characterisation and the reversible nature of these protein‐polymer conjugates are discussed, and some of the in vitro properties of these modified enzymes are explored.
