Dose-response studies on glycopyrrolate and atropine in conscious cardiac patients.
Dose-response studies on glycopyrrolate and atropine in conscious cardiac patients.
复制标题
清醒心脏病患者中格隆溴铵和阿托品的剂量反应研究。
DOI：
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发表时间：
1983
影响因子：
3.4
通讯作者：
P. Berguson
中科院分区：
文献类型：
--
作者：
D. Preiss;P. Berguson
The dose-heart rate response relationship for the two anticholinergics, atropine and glycopyrrolate, were studied in non-anaesthetised patients about to undergo coronary artery surgery. Two methods were used, the administration of increasing doses to different groups of patients, and an incremental dose technique in the same patient. Both drugs increased heart rate in a dose-related manner with glycopyrrolate being approximately twice as potent as atropine. Glycopyrrolate is as effective as atropine in correcting bradycardia prior to open heart surgery.
