FUNGAL FLORA OF NORMAL HUMAN SMALL AND LARGE INTESTINE
FUNGAL FLORA OF NORMAL HUMAN SMALL AND LARGE INTESTINE
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DOI：
10.1056/nejm196903202801204
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发表时间：
1969-01-01
影响因子：
158.5
通讯作者：
KALSER, MH
中科院分区：
文献类型：
--
作者：
COHEN, R;ROTH, FJ;KALSER, MH
27例正常成人86份（口咽23份，空肠26份，回肠20份，粪便17份）标本的培养结果表明，白色念珠菌是各地区最常见的高浓度真菌。C.白色念珠菌从口咽部到结肠逐渐增多：口咽部30%，空肠54%，回肠55%，粪便65%。在27%的口咽、43%的空肠、50%的回肠和59%的菌落样本中发现了浓度为每毫升102个菌落或更高的白色念珠菌。在最初研究后5至9个月重新采样的5名受试者中证明了小肠真菌模式的稳定性;真菌模式在定性和定量上没有变化。
Cultures of 86 specimens (including 23 oropharyngeal, 26 jejunal, 20 ileal and 17 fecal samples in 27 normal adults showedCandida albicansto be the most frequent fungus in high concentrations in all areas sampled. Both the frequency and concentration ofC. albicansincreased progressively from the oropharynx to the colon: 30 per cent in the oropharynx, 54 per cent in the jejunum, 55 per cent in the ileum and 65 per cent in the fecal specimens. C.albicans,in concentrations of 102 colonies per milliliter or greater, were encountered in 27 per cent of oropharyngeal, 43 per cent of jejunal, 50 per cent of ileal and 59 per cent of colonie specimens. The stability of the mycofloral pattern of the small intestine was demonstrated in five subjects who were resampled five to nine months after the initial studies; the fungal pattern was qualitatively and quantitatively unchanged.