A simple and inexpensive membrane "lung" for small organ perfusion.
A simple and inexpensive membrane "lung" for small organ perfusion.
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一种简单且廉价的膜“肺”，用于小器官灌注。
DOI：
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发表时间：
1974
影响因子：
6.5
通讯作者：
E. M. Severinghaus
中科院分区：
文献类型：
--
作者：
R. L. Hamilton;M. Berry;M. Williams;E. M. Severinghaus
一次性薄壁硅橡胶管线圈可渗透氧气和二氧化碳，充当“肺”，用于灌注离体大鼠肝脏。这种“肺”可以很容易地用实验室用品组装而成，与利用大型气液界面进行气体交换的装置相比，具有许多优点。通过这种简单的装置，可以实现与更复杂的氧合系统获得的肝脂蛋白甘油三酯分泌率相当的效果。
A disposable coil of thin-walled Silastic tubing, permeable to oxygen and carbon dioxide, functioned as a "lung" for perfusion of isolated rat liver. This "lung," which can be easily assembled from laboratory supplies, has a number of advantages over devices that utilize large air-liquid interfaces for gas exchange. Rates of hepatic lipoprotein triglyceride secretion, comparable to those obtained with more complex oxygenation systems, are achieved with this simple device.