Reproduction numbers for epidemic models with households and other social structures. I. Definition and calculation of R0

Reproduction numbers for epidemic models with households and other social structures. I. Definition and calculation of R0
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DOI:
10.1016/j.mbs.2011.10.009
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发表时间:
2012-01-01
影响因子:
4.3
通讯作者:
Trapman, Pieter
Trapman, Pieter
中科院分区:
生物学4区
文献类型:
--
作者:
Pellis, Lorenzo;Ball, Frank;Trapman, Pieter

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基本再生数R-0是流行病学中最重要的量之一。然而,对于具有显式社会结构的传染病模型,包括小的混合单元,如家庭,它的定义并不简单,大量的其他阈值参数已经出现在文献中。在本文中,我们使用分支过程来定义R-0,我们将此定义应用于具有家庭或其他更复杂社会结构的模型,并提供计算它的方法。All rights reserved.
The basic reproduction number R-0 is one of the most important quantities in epidemiology. However, for epidemic models with explicit social structure involving small mixing units such as households, its definition is not straightforward and a wealth of other threshold parameters has appeared in the literature. In this paper, we use branching processes to define R-0, we apply this definition to models with households or other more complex social structures and we provide methods for calculating it. (C) 2011 Elsevier Inc. All rights reserved.