Nonrandom Patterns of Mutation are Reflected in Evolutionary Divergence and May Cause Some of the Unusual Patterns Observed in Sequences
Nonrandom Patterns of Mutation are Reflected in Evolutionary Divergence and May Cause Some of the Unusual Patterns Observed in Sequences
复制标题
非随机突变模式反映在进化分歧中，可能导致序列中观察到的一些异常模式
DOI：
10.1007/978-3-642-72770-2_9
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发表时间：
1987
影响因子：
2.2
通讯作者：
G. B. Golding
中科院分区：
文献类型：
--
作者：
G. B. Golding
到目前为止，人们对自发突变知之甚少，更不知道这些随机变化如何通过选择的作用转化为有用的、适应环境的有机体。这两个过程都很复杂，因为即使是很小的突变率和小的选择系数也会在很长一段时间内产生显著的影响。这些过程将是本章的主题，尽管只有一些信息片段开始变得明显，但其中许多与普遍预期相反。
Very little is known, as yet, about spontaneous mutation and even less is known about how these random changes are translated into a useful and adapted organism through the action of selection. Both of these processes are complicated by the significant effects which even small mutation rates and small selection coefficients can have over long periods of time. These processes will be the subject of this chapter and although only some fragments of information are beginning to become apparent, many of them are contrary to common expectations.
免疫球蛋白可变基因的体细胞突变模式。
影响因子：
3.3
作者：
Golding,GB;Gearhart,PJ;Glickman,BW
通讯作者：
Glickman,BW
杂合基因和蛋白质的产生程序及其在评估同源色氨酸合成酶α多肽中氨基酸差异的显着性中的用途。
DOI：
10.1073/pnas.78.4.2169
发表时间：
1981
影响因子：
11.1
作者：
Schneider,WP;Nichols,BP;Yanofsky,C
通讯作者：
Yanofsky,C