Traumatic spreading depression syndrome. Review of a particular type of head injury in 37 patients.

Traumatic spreading depression syndrome. Review of a particular type of head injury in 37 patients.
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创伤性抑郁症蔓延。

DOI:
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发表时间:
1977
期刊:
Brain : a journal of neurology
影响因子:
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通讯作者:
K. Ando
K. Ando
中科院分区:
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文献类型:
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作者:
H. Oka;M. Kako;M. Matsushima;K. Ando

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从1476例住院的头部损伤,37例患者被选为独特的临床特征的基础上,似乎共享一个单一的和良性的病因。在这种类型的头部损伤中,轻微或相当轻微的头部损伤会导致短暂的神经系统疾病。这些疾病包括头痛、恶心和呕吐、面色苍白、嗜睡、烦躁不安、昏迷、轻偏瘫和失语症,通常在清醒间隔不到两小时后出现;然后患者恢复,或继续发展惊厥发作。儿童和青少年通常恢复无惊厥;惊厥发生在婴儿和幼儿中。这些症状不是由于脑压迫,但可能是由于自限性皮质现象。看来,惊厥发作发生在几个小时内的这种类型的头部损伤可能不是显着的创伤后癫痫的前兆。这表明,在这种类型的损伤中看到的惊厥发作和非惊厥症状之间存在密切关系,并且两者都基于具有Leão扩散性抑郁特征的共同过程。这种类型的头部损伤应被归类为一个独特的临床实体,其中不需要手术治疗,预后良好。
From 1476 hospital admissions with head injury, 37 patients were selected on the basis of distinctive clinical features which appeared to share a single and benign aetiology. In head injuries of this type, transient neurological disorders resulted from trivial or rather mild head injuries. These disorders, which included headache, nausea and vomiting, pallor, somnolence, irritability and restlessness, stupor, hemiparesis and aphasia, appeared after a lucid interval which was usually less than two hours; then the patient either recovered, or went on to develop convulsive attacks. Recovery without convulsions was usual in children and adolescents; convulsions occurred both in infants and younger children. The symptoms were not attributable to cerebral compression but were probably due to a self-limiting cortical phenomenon. It appears that convulsive attacks occurring within a few hours of this type of head injury may not be significant as precursors of post-traumatic epilepsy. It is suggested that there is a close relation between the convulsive attacks and the non-convulsive symptoms seen in this type of injury and that both are based on a common process which has the characteristics of the spreading depression of Leão. This type of head injury should be classified as a distinct clinical entity, in which no surgical treatment is required and the prognosis is good.