Progress towards understanding the neurobiology of Batten disease or neuronal ceroid lipofuscinosis.

Progress towards understanding the neurobiology of Batten disease or neuronal ceroid lipofuscinosis.
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了解巴顿病或神经元蜡质脂褐质沉积症的神经生物学进展。

DOI:
10.1097/01.wco.0000063762.15877.9b
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发表时间:
2003
影响因子:
4.8
通讯作者:
Cooper,JonathanD
Cooper,JonathanD
中科院分区:
医学2区
文献类型:
--
作者:
Cooper,JonathanD

文献摘要

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对疾病机制的深入了解正在建立神经元蜡样质脂褐质沉积症对大脑影响的详细资料。随着开发成功的治疗策略的最终目标,同样重要的是表征疾病的临床进展,并确定最终可用于临床试验的可量化终点。
Insights into disease mechanisms are building a detailed profile of the impact of neuronal ceroid lipofuscinosis upon the brain. With the eventual aim of developing successful therapeutic strategies, it will be equally important to characterize the clinical progression of the disorder, and to identify quantifiable endpoints that can ultimately be used in clinical trials.