Pediatric Obesity, Hypertension, Lipids.
Pediatric Obesity, Hypertension, Lipids.
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DOI：
10.1007/s40746-020-00188-2
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发表时间：
2020-06
影响因子：
--
通讯作者：
Zachariah JP
中科院分区：
文献类型：
--
作者：
Leopold S;Zachariah JP
在过去的40年里，儿童肥胖症流行的增加使人们更加关注儿童肥胖、高血压和血脂异常的管理。多项研究表明，这些风险因素从儿童期到成年期都有影响，使个体易患过早的动脉粥样硬化性心血管疾病，并使他们处于早期发病和死亡的风险之中。重要的是，肥胖、高血压和血脂问题是可以独立发生的个体风险因素。多项研究表明，每种危险因素都会导致儿童靶器官损伤。密集和集中的生活方式改变可以改善儿童的亚临床疾病，降低未来发病的风险。儿童时期为动脉粥样硬化性心血管疾病的原始和一级预防提供了独特的机会。临床医生必须专注于针对这些高度流行的疾病和应用生活方式的改变，然后根据需要进行药物或手术治疗。
The rise of the pediatric obesity pandemic over the past 40 years has sharpened focus on the management of obesity, hypertension and lipid abnormalities in children. Multiple studies demonstrate that these risk factors track from childhood into adulthood predisposing individuals to premature atherosclerotic cardiovascular disease and putting them at risk for early morbidity and mortality. Importantly, obesity, hypertension and lipid problems are individual risk factors that can occur independently. Multiple studies have shown that each risk factor causes target organ damage in children. Intensive and focused lifestyle modifications can improve a child’s subclinical disease and decrease the risk for future morbidity. Childhood offers a unique opportunity at primordial and primary prevention of atherosclerotic cardiovascular disease. Clinicians must focus on targeting these highly prevalent conditions and applying lifestyle modification and then pharmacologic or surgical therapies as needed.