A population-based survey of eczema prevalence in the united states
A population-based survey of eczema prevalence in the united states
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DOI：
10.2310/6620.2007.06034
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发表时间：
2007-06-01
期刊：
影响因子：
5.2
通讯作者：
Reed, Michael L.
中科院分区：
文献类型：
--
作者：
Hanifin, Ion M.;Reed, Michael L.
背景湿疹和特应性皮炎（AD）是世界范围内公认的主要健康问题。患病率估计高达三分之一的人口，这取决于研究的国家，受试者的年龄范围和使用的诊断标准。美国populations.Objective：要检查湿疹，AD和湿疹的条件，在美国通过分析疾病和症状的患病率，估计未确诊病例的数量，并评估comorbidity.Methods：一个自我管理的问卷调查所带来的公共卫生问题发送到一个样本的家庭（N = 60,000）代表美国人口。一名指定的成员回答了有关症状、诊断和对受影响家庭成员的影响的信息; 42，249户家庭（70%）回答了问题，代表116，202人。经验性湿疹定义为瘙痒/抓挠和红色/发炎皮疹或过度干燥/脱屑。经验性AD定义为瘙痒/抓挠和红色/发炎皮疹、过度干燥/脱屑、皮褶部位、早期发作、症状持续！14天，或哮喘或过敏性鼻炎或hayfever.Results的医生诊断：研究的人群中，17.1%的报告至少有一个四湿疹症状，经验定义的湿疹被发现在10.7%，经验定义的AD被发现在6%。患病率随着收入的增加而下降。大约三分之二的湿疹或AD经验性诊断患者有中度至重度症状，三分之一有睡眠障碍，四分之一有慢性持续症状。超过三分之一（37.19/6）的有症状的人报告了医生诊断。经验性AD的发病高峰出现在年龄
Background Eczema and atopic dermatitis (AD) are recognized as major health problems worldwide. Prevalence estimates are as high as one-third of the population, depending on the country studied, the age range of the subjects, and the diagnostic criteria used. National estimates of prevalence for the US population are lacking.Objective: To examine the public health problem posed by eczema, AD, and eczematous conditions in the United States by analyzing disease and symptom prevalence, estimating the number of undiagnosed cases, and assessing comorbidities.Methods: A self-administered questionnaire was sent to a sample of households (N = 60,000) representative of the US population. A designated member responded with information on symptoms, diagnoses, and impact for affected household members; 42,249 households (70%) responded, representing 116,202 individuals. Empirical eczema was defined by itching/scratching and red/inflamed rash or excessive dryness/scaling. Empirical AD was defined by itching/scratching and red/inflamed rash, excessive dryness/scaling, skinfold location, early onset, symptoms lasting ! 14 days, or a physician diagnosis of asthma or of allergic rhinitis or hay fever.Results: Of the population studied, 17.1% reported at least one of four eczematous symptoms; empirically defined eczema was found in 10.7%, and empirically defined AD was found in 6%. Prevalence decreased with increasing income. Approximately two-thirds of individuals with an empirical diagnosis of eczema or AD had moderate to severe symptoms, one-third had sleep disturbances, and one-quarter had chronic unremitting symptoms. Just over one-third (37.19/6) of those with symptoms reported a physician diagnosis. Peak onset for empirical AD occurred in the group of subjects aged