PREVALENCE OF VENTRICULOMEGALY IN ASSOCIATION WITH MYELOMENINGOCELE - CORRELATION WITH GESTATIONAL-AGE AND SEVERITY OF POSTERIOR-FOSSA DEFORMITY
PREVALENCE OF VENTRICULOMEGALY IN ASSOCIATION WITH MYELOMENINGOCELE - CORRELATION WITH GESTATIONAL-AGE AND SEVERITY OF POSTERIOR-FOSSA DEFORMITY
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DOI：
10.1148/radiology.190.3.8115615
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发表时间：
1994-03-01
期刊：
影响因子：
19.7
通讯作者：
FILLY, RA
中科院分区：
文献类型：
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作者：
BABCOOK, CJ;GOLDSTEIN, RB;FILLY, RA
目的：探讨脑室扩大 (VM) 与胎龄 (GA) 以及相关 Chiari II 畸形严重程度的关系。材料和方法：对 51 例脊髓脊膜膨出胎儿的超声检查进行回顾性分析。当心室横径大于10mm时判断存在VM。后颅窝（PF）畸形的严重程度主观分级为轻度、中度或重度。 34 名胎儿在 GA 小于或等于 24 周时进行扫描，17 名胎儿在 GA 24 周以上时进行扫描。 结果：VM 患病率为 61%。然而，只有 44% 小于或等于 24 周 GA 的胎儿患有 VM，而 94% >24 周 GA 的胎儿患有 VM。与轻度 PF 畸形的胎儿相比，中度或重度畸形的胎儿 VM 和最大脑室的患病率较高。结论：脊髓脊膜膨出胎儿中 VM 的患病率随 GA 和相关 PF 畸形的严重程度而变化。一旦超声检查检测到脊髓脊膜膨出，这些观察结果可能会提供额外的预后信息。
PURPOSE: To investigate the relationship of ventriculomegaly (VM) with gestational age (GA) and the severity of the associated Chiari II malformation.MATERIALS AND METHODS: The sonograms of 51 fetuses with myelomeningoceles were retrospectively: reviewed. VM was judged to be present when the transverse ventricular atrial diameter was greater than 10 mm. The severity of the posterior fossa (PF) deformity was subjectively graded as mild, moderate, or severe. Thirty-four fetuses were scanned at less than or equal to 24 weeks GA, and 17 were scanned at >24 weeks GA.RESULTS: The prevalence of VM was 61%. However, only 44% of fetuses less than or equal to 24 weeks GA had VM, whereas 94% of fetuses >24 weeks GA had VM. When compared with fetuses with mild PF deformities, fetuses with moderate or severe deformities had a higher prevalence of VM and the largest ventricles.CONCLUSION: The prevalence of VM in fetuses with myelomeningoceles varies with both GA and the severity of the associated PF deformity. These observations may provide additional prognostic information once a myelomeningocele is detected at sonography.