MRSA at an English children’s hospital from 1998 to 2003
MRSA at an English children’s hospital from 1998 to 2003
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1998 年至 2003 年英国一家儿童医院的 MRSA
DOI：
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发表时间：
2005
影响因子：
5.2
通讯作者：
J. Gray
中科院分区：
文献类型：
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作者：
A. Adedeji;J. Gray
目的：研究MRSA的流行病学和临床方面，在医院出现的门诊病人中：人口统计学，流行病学和临床数据的分析，在1998年1月至2003年12月在250张床英语之间收集的385名儿童儿童医院90例在31个病例中发生。医院以前曾在医院出任MRSA的13.9％的住院患者。在专业之间，血管内装置是MRSA细菌的最常见来源（63.4％的病例）。 MRSA的收购和细菌血症的案例之间没有联系，这表明MRSA的增加可能不仅反映了英国儿童的MRSA患病率的增加。
Aims: To investigate the epidemiological and clinical aspects of MRSA among inpatients and outpatients presenting to hospital. Methods: Analysis of demographic, epidemiological, and clinical data collected on 385 children first identified as having MRSA between January 1998 and December 2003 in a 250 bed English children’s hospital. Results: There were 267 inpatients and 118 outpatients. The number of new cases of MRSA declined from 72 in 1998 to 52 in 2003, whereas hospital activity increased. Ninety nine (37.1%) inpatients acquired MRSA outside the hospital; a further 90 occurred among 31 clusters of cases. One hundred and seventy eight (66.7%) inpatients were aged <2 years; cardiac services and paediatric & neonatal surgery accounted for 59.6% of cases. Dermatology and A&E accounted for 51.7% of outpatients; 73.8% of outpatients had recently previously attended the hospital. A total of 13.9% of inpatients with MRSA developed bacteraemia; MRSA accounted for 15% of Staphylococcus aureus bacteraemias. The risk of MRSA bacteraemia in colonised patients, and the proportion of S aureus bacteraemias that were MRSA, varied between specialties. Intravascular devices were the most common source of MRSA bacteraemia (63.4% of cases). The mortality rate was 7.3%. Conclusions: Enhanced surveillance of MRSA can identify at-risk patient groups, thus facilitating targeting of control measures. The absence of a link between numbers of cases of acquisition of MRSA and bacteraemia suggests that the rise in MRSA bacteraemia may not solely reflect an increase in MRSA prevalence in children in the UK. The need for larger epidemiological studies is emphasised.