Synthesis of benzocycloheptanones through coupling of δ,ε-unsaturated chromium carbene complexes and 2-alkynylbenzoyl derivatives.
Synthesis of benzocycloheptanones through coupling of δ,ε-unsaturated chromium carbene complexes and 2-alkynylbenzoyl derivatives.
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通过 δ,δ-不饱和铬卡宾配合物和 2-炔基苯甲酰衍生物的偶联合成苯并环庚酮。
DOI：
10.1021/ol200825j
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发表时间：
2011
期刊：
影响因子：
5.2
通讯作者：
Herndon,JamesW
中科院分区：
文献类型：
--
作者：
Patti,RajeshKumar;Waynant,KristopherV;Herndon,JamesW
戊烯基卡宾配合物和2-炔基苯甲酰基衍生物的偶联一步即可得到萘并环庚酮，涉及同时构建七元环和其中一个芳环。芳基系链系统经历分子内环丙烷化。
The coupling of pentenylcarbene complexes and 2-alkynylbenzoyl derivatives affords naphthocycloheptanones in a single step involving simultaneous construction of both the seven-membered ring and one of the aromatic rings. Aryl tethered systems undergo intramolecular cyclopropanation.