THE RELATIONSHIP BETWEEN ESTROGEN-LEVELS AND DIETS OF CAUCASIAN AMERICAN AND ORIENTAL IMMIGRANT WOMEN
THE RELATIONSHIP BETWEEN ESTROGEN-LEVELS AND DIETS OF CAUCASIAN AMERICAN AND ORIENTAL IMMIGRANT WOMEN
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DOI：
10.1093/ajcn/44.6.945
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发表时间：
1986-12-01
影响因子：
7.1
通讯作者：
GERSHOFF, SN
中科院分区：
文献类型：
--
作者：
GOLDIN, BR;ADLERCREUTZ, H;GERSHOFF, SN
研究人员在两组饮食习惯与乳腺癌风险不同的女性中研究了饮食与雌激素之间的关系。测定了绝经前、绝经后白种人和新近从东南亚移居夏威夷的东方移民的血浆雌激素和雄激素水平，以及24小时尿液和粪便中雌激素的排泄量。绝经前高加索人的血浆雌二醇和雌二醇水平比夏威夷同龄人群高30-75%，绝经后高加索人的血浆雌二醇水平比同龄人群高3倍。东方女性在粪便中排出的雌激素是男性的两倍多，但在尿液中排出的雌激素却少得多。因此，尿粪排泄比约为。在年轻的白种人女性中是3-5倍。对绝经前妇女膳食成分和血浆雌激素的分析表明，每日总脂肪和饱和脂肪摄入量与血浆雌激素和雌二醇浓度呈正相关。
The relationship between diet and estrogens was studied in two groups of women with different dietary habits and breast cancer risks. Plasma estrogens and androgens and 24-h urinary and fecal excretion of estrogens were measured in premenopausal and postmenopausal caucasians and recent Oriental immigrants from Southeast Asia to Hawaii. Premenopausal Caucasian had 30-75% higher plasma estrone and estradiol levels than their age-matched cohorts in Hawaii, and the postmenopausal Caucasians had 3-fold higher plasma levels of estradiol. The Oriental women excreted more than twice the amount of estrogen in their feces but they excreted significantly less in their urine. Thus, the ratio of urinary-to-fecal excretion was .apprx. 3-5 times higher in young Caucasian women. Analysis of dietary components and plasma estrogens in premenopausal women showed a positive correlation between daily intake of total fat and saturated fat and plasma estrone and estradiol concentrations.