Current Status of Organ Preservation in Carcinoma Larynx.
Current Status of Organ Preservation in Carcinoma Larynx.
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DOI：
10.14740/wjon1105w
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发表时间：
2018-04
影响因子：
5.2
通讯作者：
Kainickal CT
中科院分区：
文献类型：
--
作者：
Bhattacharyya T;Kainickal CT
喉癌的器官保留是一个长期争论的话题。喉癌的治疗可根据不同的因素选择多种保留器官的方法。根治性放射治疗（RT）和保留喉手术在早期喉癌中显示出相同的结果。同步放化疗（CTRT）是软骨完整、喉功能正常的III期和IV期喉癌的标准治疗方法。软骨破坏或喉功能障碍的患者不适合保留器官。本系统综述旨在讨论不同器官保留方法的演变，其有效性，对语音质量的影响，其缺陷和未来的发展方向。
Organ preservation in carcinoma larynx is a long debated topic. There are multiple organ preserving approaches in the management of carcinoma larynx depending on various factors. Radical radiotherapy (RT) and conservation laryngeal surgery have shown equivalent results in early laryngeal cancer. Concurrent chemoradiation (CTRT) is the standard treatment in stage III and IV laryngeal cancer with intact cartilage and functional larynx. Patients with cartilage destruction or dysfunctional larynx are not the candidates for organ preservation. This systematic review is aimed at discussing the evolution of different organ preserving approaches, their efficacy, impact on voice quality, their pitfalls and future directions.