Acute Kidney Injury in the Cancer Patient
Acute Kidney Injury in the Cancer Patient
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DOI：
10.1053/j.ackd.2013.08.002
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发表时间：
2014-01-01
影响因子：
2.9
通讯作者：
Okusa, Mark D.
中科院分区：
文献类型：
--
作者：
Campbell, G. Adam;Hu, Daniel;Okusa, Mark D.
急性肾损伤（AKI）是癌症和癌症治疗中一种常见且重要的并发症。癌症患者经常遇到AKI的危险因素，包括年龄较大，CKD，前列腺疾病，败血症，暴露于肾毒素和阻塞性生理。AKI也可继发于副肿瘤疾病，包括肾小球肾炎和微血管病变。这种并发症可产生严重后果，包括影响患者继续接受恶性肿瘤治疗的能力。这篇综述将有助于总结癌症患者中存在的AKI的潜在病因，并强调特定的患者群体，如危重癌症患者。(C) 2014年由国家肾脏基金会，Inc。版权所有。
Acute kidney injury (AKI) is a frequent and significant complication of cancer and cancer therapy. Cancer patients frequently encounter risk factors for AKI including older age, CKD, prerenal conditions, sepsis, exposure to nephrotoxins, and obstructive physiology. AKI can also be secondary to paraneoplastic conditions, including glomerulonephritis and microangiopathic processes. This complication can have significant consequences, including effects on patients' ability to continue to receive therapy for their malignancy. This review will serve to summarize potential etiologies of AKI that present in patients with cancer as well as to highlight specific patient populations, such as the critically ill cancer patient. (C) 2014 by the National Kidney Foundation, Inc. All rights reserved.