EFFECT OF COLD EXPOSURE ON METABOLISM OF UBIQUINONE IN RAT
EFFECT OF COLD EXPOSURE ON METABOLISM OF UBIQUINONE IN RAT
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DOI：
10.1016/0005-2728(68)90214-4
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发表时间：
1968-01-01
期刊：
影响因子：
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通讯作者：
RAMASARMA, T
中科院分区：
文献类型：
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作者：
AITHAL, HN;JOSHI, VC;RAMASARMA, T
1.暴露于寒冷环境的大鼠肝脏中泛醌的积累被证明是由于整个实验期间分解代谢减少和中间阶段（10-20天）合成增加所致。2．当泛醌在暴露 40 天后（与适应环境一致）在肝脏中积累时，或者通过吸收外源性饮食供应（可能是通过终产物调节机制），寒冷暴露大鼠中增加的内源合成被消除。
1. Accumulation of ubiquinone in the livers of rats exposed to a cold environment was shown to be due to both decreased catabolism during the entire experimental period and increased synthesis during an intermediate stage (10–20 days).2. The increased endogenous synthesis in the cold-exposed rats was eliminated when ubiquinone accumulated in the liver after exposure for 40 days (coinciding with acclimatization), or by absorption of the exogenous dietary supply, possibly by the mechanism of end-product regulation.