UV-guided isolation of alantrypinone, a novel Penicillium alkaloid

UV-guided isolation of alantrypinone, a novel Penicillium alkaloid
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DOI:
10.1021/np980056v
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发表时间:
1998-09-01
影响因子:
5.1
通讯作者:
Christophersen, C
Christophersen, C
中科院分区:
生物学2区
文献类型:
--
作者:
Larsen, TO;Frydenvang, K;Christophersen, C

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烟喹唑啉F(1)和丙氨色酮(2)是胸腺青霉的两种主要代谢产物。2的结构,其中包含一个新的环结构,通过分析光谱数据,包括2D NMR的解析。通过单晶X射线衍射研究确定了2的绝对构型。
Fumiquinazoline F (1) and alantrypinone (2) have been isolated as the two major metabolites of Penicillium thymicola. The structure of 2, which contains a new ring structure, was elucidated by analysis of spectroscopic data including 2D NMR. The absolute configuration of 2 was established by a single-crystal X-ray diffraction study.