Beta-palmitate - a natural component of human milk in supplemental milk formulas.
Beta-palmitate - a natural component of human milk in supplemental milk formulas.
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DOI：
10.1186/s12937-016-0145-1
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发表时间：
2016-03-17
影响因子：
5.4
通讯作者：
Kuchta M
中科院分区：
文献类型：
--
作者：
Havlicekova Z;Jesenak M;Banovcin P;Kuchta M
人乳的成分和功能是独特的，并为现代人工配方奶的开发提供了基础，可以为非母乳喂养的婴儿提供适当的替代品。虽然人乳不能完全替代，但现代配方奶正试图模仿人乳，并部分替代其对婴儿的复杂生物积极作用。除了来自人乳的免疫调节因子外，研究还集中在具有高含量β-棕榈酸（sn-2棕榈酸，β-棕榈酸酯）的人乳脂肪的组成和结构上。根据现有的研究，增加添加到配方奶粉中的β-棕榈酸酯的含量可以促进几种有益的生理功能。β-棕榈酸酯积极影响脂肪酸代谢，增加钙吸收，改善骨基质质量和粪便稠度，并对肠道微生物组的发育产生积极影响。
The composition and function of human milk is unique and gives a basis for the development of modern artificial milk formulas that can provide an appropriate substitute for non-breastfed infants. Although human milk is not fully substitutable, modern milk formulas are attempting to mimic human milk and partially substitute its complex biological positive effects on infants. Besides the immunomodulatory factors from human milk, research has been focused on the composition and structure of human milk fat with a high content of β-palmitic acid (sn-2 palmitic acid, β-palmitate). According to the available studies, increasing the content of β-palmitate added to milk formulas promotes several beneficial physiological functions. β-palmitate positively influences fatty acid metabolism, increases calcium absorption, improves bone matrix quality and the stool consistency, and has a positive effect on the development of the intestinal microbiome.