Quality of life and mental health in cervical and endometrial cancer survivors
Quality of life and mental health in cervical and endometrial cancer survivors
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DOI：
10.1016/j.ygyno.2005.08.023
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发表时间：
2006-03-01
影响因子：
4.7
通讯作者：
Anderson, B
中科院分区：
文献类型：
--
作者：
Bradley, S;Rose, S;Anderson, B
目标。本研究的目的是检查宫颈癌和子宫内膜癌长期幸存者的生活质量和情绪。生活质量和情绪与人口统计学和疾病因素的关系也进行了调查。152名5-20年前在爱荷华大学医院和诊所诊断和治疗的宫颈癌或子宫内膜癌幸存者参与了研究。从某医院妇科门诊招募89名健康对照者。生活质量、情绪和人口统计数据通过问卷进行评估。从医疗记录中提取癌症幸存者的疾病特征。三组患者的生活质量和抑郁症状没有显著差异。宫颈癌幸存者比子宫内膜癌幸存者更焦虑，比子宫内膜癌幸存者或健康对照组更烦躁、愤怒和困惑。据报道，失业和未婚的癌症幸存者更容易抑郁和情绪紊乱。治疗方式、疾病分期和诊断后的时间与生活质量或情绪无关。宫颈癌和子宫内膜癌幸存者在诊断后5年的生活质量与健康对照接近。然而，与子宫内膜癌幸存者或健康对照者相比，宫颈癌幸存者报告的负面情绪更多。失业或独居的癌症幸存者可能特别容易出现情绪和精神健康问题。(C) 2005爱思唯尔公司版权所有。
Objectives. The goal of this study was to examine quality of life and mood in long-term survivors of cervical and endometrial cancer. Relationships of quality of life and mood with demographic and disease factors were also investigated.Methods. One-hundred fifty-two survivors of cervical or endometrial cancer diagnosed and treated 5-20 years ago at the University of Iowa Hospitals and Clinics participated. Eighty-nine healthy controls were recruited from a hospital gynecology clinic. Quality of life, mood, and demographics were assessed by questionnaires. Disease characteristics of cancer survivors were abstracted from medical records.Results. There were no significant differences in quality of life or depressive symptoms between the three groups. Cervical cancer survivors reported significantly more anxiety than endometrial cancer survivors, and more dysphoria, anger, and confusion than either endometrial cancer survivors or healthy controls. Greater depression and mood disturbance were reported by unemployed and unmarried cancer survivors. Treatment modality, stage of disease, and length of time since diagnosis were not related to quality of life or mood.Conclusions. Quality of life in cervical and endometrial cancer survivors approximates that of healthy controls by 5 years post-diagnosis. However, cervical cancer survivors report more negative mood than survivors of endometrial cancer or healthy controls. Cancer survivors who are unemployed or living alone may be especially at risk for mood and mental health difficulties. (C) 2005 Elsevier Inc. All rights reserved.