Esophageal dysmotility in patients who have eosinophilic esophagitis.
Esophageal dysmotility in patients who have eosinophilic esophagitis.
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DOI：
10.1016/j.giec.2007.09.006
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发表时间：
2008-01-01
影响因子：
--
通讯作者：
Rosen, Rachel
中科院分区：
文献类型：
--
作者：
Nurko, Samuel;Rosen, Rachel
尽管嗜酸粒细胞性食管炎（EE）患者常见吞咽困难，但对食管运动改变的了解仍处于起步阶段。据报道，EE 患者存在多种运动障碍，包括贲门失弛缓症、弥漫性食管痉挛、胡桃夹食管和非特异性运动改变，包括食管体大幅收缩、三次收缩、食管下端括约肌压力异常和其他蠕动问题。一些证据表明 EE 治疗可以改善运动能力。高分辨率测压法和与阻抗相结合的测压法等技术进步可能会为更细微的运动异常提供新的见解。
The understanding of esophageal motility alterations in patients who have eosinophilic esophagitis (EE) is in its infancy despite the common presenting complaint of dysphagia. A diversity of motility disorders has been reported in patients who have EE including achalasia, diffuse esophageal spasm, nutcracker esophagus, and nonspecific motility alterations including high-amplitude esophageal body contractions, tertiary contractions, abnormalities in lower esophageal sphincter pressure, and other peristaltic problems. Some evidence suggests that treatment of EE will improve motility. Technological advances such as high-resolution manometry and combined manometry with impedance may provide new insight into more subtle motility abnormalities.