Legionella pneumophila serogroup 1 isolates from cooling towers in Japan form a distinct genetic cluster

Legionella pneumophila serogroup 1 isolates from cooling towers in Japan form a distinct genetic cluster
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DOI:
10.1111/j.1348-0421.2005.tb03699.x
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发表时间:
2005-01-01
影响因子:
2.6
通讯作者:
Watanabe, H
Watanabe, H
中科院分区:
医学4区
文献类型:
--
作者:
Amemura-Maekawa, J;Kura, F;Watanabe, H

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采用脉冲场凝胶电泳(PFGE)和基于序列的分型(SBT)技术,对31株与流行病学无关的嗜肺军团菌血清1型分离株(10株来自冷却塔,10株来自公共温泉和/或温泉浴场,11株来自患者)进行了分析,使用6个位点flaA、pilE、asd、mip、mompS和proA。PFGE和SBT分析结果表明,10株冷却塔分离菌聚为一个独特的类型,与其他环境来源的菌株不同。
Thirty-one epidemiologically unrelated Legionella pneumophila serogroup 1 isolates (10 from cooling towers, 10 from public spas and/or hot spring baths, and 11 from patients) were analyzed by pulsed-field gel electrophoresis (PFGE) and sequence-based typing (SBT) using 6 loci,flaA,pilE, asd, mip, mompS, and proA. The results of PFGE and SBT analysis indicated that all 10 isolates from cooling towers clustered into a unique type, which was distinct from strains of other environmental sources.