BED NETS FOR THE PREVENTION OF MALARIA AND ANEMIA IN PREGNANCY
BED NETS FOR THE PREVENTION OF MALARIA AND ANEMIA IN PREGNANCY
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DOI：
10.1016/0035-9203(93)90262-o
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发表时间：
1993-11-01
影响因子：
2.2
通讯作者：
NOSTEN, F
中科院分区：
文献类型：
--
作者：
DOLAN, G;TERKUILE, FO;NOSTEN, F
对居住在泰缅边境疟疾中度流行区的341名孕妇进行了蚊帐抗疟效果的前瞻性比较。3个相邻研究地点的妇女被随机分配接受单一尺寸的氯菊酯浸渍蚊帐（PIB），非浸渍蚊帐（NIB），或对照组使用自己的家庭尺寸的非未浸渍蚊帐（FNIB）或不使用蚊帐。在一个研究地点，而不是其他2个，PIB显着降低寄生虫密度，并与FNIB一起，降低疟疾的发病率在怀孕期间从56%到33%（相对风险=1.67，置信区间=1.07-2.61，P=0.03，考虑到奇偶校验）。事实证明，贫血是比寄生虫率更敏感的蚊帐抗疟效果标志。贫血的发生率（红细胞压积
A prospective comparison of the antimalarial efficacy of bed nets was conducted with 341 pregnant women living in a mesoendemic malarious area of the Thai-Burmese border. Women in 3 adjacent study sites were allocated at random to receive either a single size permethrin-impregnated bed net (PIB), a non-impregnated bed net (NIB), or to a control group who used either their own family size non-unpregnated bed net (FNIB) or no net. In one study site, but not the other 2, PIB significantly reduced parasite densities and, together with FNIB, reduced the incidence of malaria in pregnancy from 56% to 33% (relative risk=1.67, confidence interval=1.07-2.61, P=0.03, allowing for parity). Anaemia proved a more sensitive marker of bed net antimalarial efficacy than parasite rates. The incidence of anaemia (haematocrit