Ultrasonic tissue characterization of renal cell carcinoma tissue.
Ultrasonic tissue characterization of renal cell carcinoma tissue.
复制标题
肾细胞癌组织的超声组织表征。
作者：
H. Sasaki;M. Tanaka;Y. Saijo;H. Okawai;Y. Terasawa;S. Nitta;K. Suzuki
本研究的目的是通过测量微声特性来表征肾细胞癌组织。采用扫描声显微镜系统，在100-200 MHz的频率范围内测量了二维分布上的衰减常数和声速。两种癌细胞的衰减常数和声速值均低于正常肾细胞，但透明细胞和颗粒细胞之间无显著差异。肿瘤细胞的声学参数均明显低于出血细胞和纤维化细胞。这些数据提示肾细胞癌组织的弹性可能低于正常肾组织。此外，临床超声显示的高强度回声可能与癌组织微声场的不均匀性有关。
The purpose of this study was to characterize renal cell carcinoma tissue by the measurement of microacoustic properties. A scanning acoustic microscope system operating in the frequency range of 100-200 MHz was employed and the attenuation constant and sound speed were measured on the two-dimensional distribution. The values of attenuation constant and sound speed were lower in both kinds of cancer cells than those in normal kidney, although a significant difference was not found between the clear cell and granular cell. Also, both acoustic parameters of cancer cells were significantly lower than those in hemorrhage and fibrosis. These data suggest that the elasticity of renal cell carcinoma tissue may be lower than that of normal kidney. Moreover, the high intensity echo in clinical echography may be related to the heterogeneity of the microacoustic field in the carcinoma tissue.