Age-related changes of the MR appearance of CNS involvement in neurocutaneous melanosis complex
Age-related changes of the MR appearance of CNS involvement in neurocutaneous melanosis complex
复制标题
神经皮肤黑变病复合体中枢神经系统受累的 MR 表现与年龄相关的变化
DOI：
10.1007/s002470000348
复制
发表时间：
2000
影响因子：
2.3
通讯作者：
T. Hara
中科院分区：
文献类型：
--
作者：
K. Gondo;R. Kira;Y. Tokunaga;T. Hara
摘要我们报告一例巨大先天性黑色素细胞痣（GCMN）的风险发展神经皮肤黑变病（NCM）与年龄相关的变化可观察到的大脑MRI。然而，虽然磁共振成像在NCM中的有用性是众所周知的，但很少报告MRI上与年龄相关的变化。GCMN伴癫痫和/或精神发育迟滞的阳性MRI结果的患病率和预后有待澄清。本病例报告可能表明连续脑MRI在GCMN病例中评估NCM风险的重要性。
Abstract We report a case of giant congenital melanocytic nevi (GCMN) at risk of developing neurocutaneous melanosis (NCM) with age-related changes observable on MRI of the brain. However, although the usefulness of MR imaging in NCM is well known, age-related changes on MRI have rarely been reported. The prevalence of positive MRI findings and prognosis in GCMN accompanied by epilepsy and/or mental retardation awaits clarification. This case report may suggest the importance of serial brain MRI in cases of GCMN in assessing the risk of NCM.