MEMBRANE TRANSPORT PROTEINS IMPLICATIONS OF SEQUENCE COMPARISONS
MEMBRANE TRANSPORT PROTEINS IMPLICATIONS OF SEQUENCE COMPARISONS
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DOI：
10.1016/0955-0674(92)90090-y
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发表时间：
1992-01-01
影响因子：
7.5
通讯作者：
HENDERSON P J F
中科院分区：
文献类型：
--
作者：
GRIFFITH J K;BAKER M E;HENDERSON P J F
对许多转运蛋白的序列和结构的分析表明，它们在底物特异性、转运方向和转运机制方面不同，这表明它们形成了一个相关蛋白家族。它们的序列相似性意味着共同的作用机制。这一假设提供了一个客观的基础，检查其作用机制和其他转运蛋白的关系。
Analyses of the sequences and structures of many transport proteins that differ in substrate specificity, direction of transport and mechanism of transport suggest that they form a family of related proteins. Their sequence similarities imply a common mechanism of action. This hypothesis provides an objective basis for examining their mechanisms of action and relationships to other transporters.