A POSS-based supramolecular amphiphile and its hierarchical self-assembly behaviors.
A POSS-based supramolecular amphiphile and its hierarchical self-assembly behaviors.
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DOI：
10.1002/marc.201100877
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发表时间：
2012-05
影响因子：
4.6
通讯作者：
Binbin Jiang;Wei Tao;Xin Lu;Yong Liu;Haibao Jin;Yan Pang;Xiaoyi Sun;D. Yan;Yongfeng Zhou
中科院分区：
文献类型：
--
作者：
Binbin Jiang;Wei Tao;Xin Lu;Yong Liu;Haibao Jin;Yan Pang;Xiaoyi Sun;D. Yan;Yongfeng Zhou
采用单金刚烷功能化POSS （AD-POSS）与β-环糊精低聚物P（β-CD）的主客体包合反应制备了基于多面体寡聚硅氧烷（POSS）的超分子两亲化合物。在H(2)O/甲苯界面的辅助下，获得的超分子杂化物自组装成稳定的空心厚壁纳米球。通过自旋涂层技术，这些中空的纳米球聚集在一起，形成一个球体层，然后进一步转化为含有纳米级孔的薄多孔膜。空心纳米球具有较低的细胞毒性。体外细胞培养结果表明，纳米孔膜能促进细胞的粘附和增殖。通过扫描电镜（SEM）、透射电镜（TEM）、原子力显微镜（AFM）、能谱分析（DLS）、能谱分析（XPS）和水接触角测试对自组装的形貌和结构进行了表征，并对自组装机理进行了探讨。
A polyhedral oligomeric silsesquioxane (POSS)-based supramolecular amphiphile is prepared from the host-guest inclusion complexation between a mono adamantane-functionalized POSS (AD-POSS) and a β-cyclodextrin oligomer (P(β-CD)). Assisted by the interface of H(2)O/toluene, the obtained supramolecular hybrids self-assemble into stable hollow nanospheres with thick walls. These hollow nanospheres aggregate together into a sphere layer through a spin coating technique, which then further transforms into a thin porous film containing nanometer-scale holes. The hollow nanospheres have a low cytotoxicity. The in vitro cell culture indicates the nanoporous films promote adhesion and proliferation of cells. The self-assembly morphologies and structures have been carefully characterized by SEM, TEM, AFM, DLS, XPS and water-contact angle measurements, and the self-assembly mechanism has also been discussed.