The relationship of psychiatric comorbidity to treatment outcomes in methadone maintained patients
The relationship of psychiatric comorbidity to treatment outcomes in methadone maintained patients
复制标题
DOI：
10.1016/s0376-8716(00)00148-4
复制
发表时间：
2001-02-01
影响因子：
4.2
通讯作者：
Mulvaney, FD
中科院分区：
文献类型：
--
作者：
Cacciola, JS;Alterman, AI;Mulvaney, FD
作者研究了278例美沙酮维持治疗患者的共病非物质使用精神障碍与入院前问题状态和治疗结果的关系。根据结构化诊断访谈，最近入院的患者被分配到DSM-III-R轴I和II诊断。成瘾严重程度指数在入院时进行评估，以评估过去和目前的物质使用和心理社会问题，并再次7个月后。还获得了治疗保留和第7个月药物尿分析结果。在物质使用和心理社会领域，无论合并症如何，参与者都表现出显着和可比的改善水平。合并症的参与者接受了更多的同时精神科治疗，这可能是各组之间缺乏差异改善的原因。尽管如此。精神共病与入院和随访时较差的心理社会和医疗状况相关，合并轴I和轴II共病的参与者问题最严重。入院和7个月的物质使用，在大多数情况下。与精神共病无关，尽管有趋势表明人格障碍参与者的治疗损耗更多。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
The authors examined the relationship of comorbid non-substance use psychiatric disorders to preadmission problem status and treatment outcomes in 278 methadone maintenance patients. Recent admissions were assigned DSM-III-R Axis I and II diagnoses according to structured diagnostic interviews. The Addiction Severity Index was administered at admission to assess past and current substance use and psychosocial problems and again 7 months later. Treatment retention and month 7 drug urinalysis results were also obtained. Across substance use and psychosocial domains, participants showed significant and comparable levels of improvement regardless of comorbidity. Comorbid participants received more concurrent psychiatric treatment which may have accounted for the lack of differential improvement among groups. Nevertheless. psychiatric comorbidity was associated with poorer psychosocial and medical status at admission and follow-up and participants with the combination of Axis I and II comorbidity had the most severe problems. Admission and month 7 substance use were, for the most part. not related to psychiatric comorbidity, although there was a trend indicating more treatment attrition for participants with personality disorders. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.