Sexually transmitted infections among female sex workers in Yunnan, China
Sexually transmitted infections among female sex workers in Yunnan, China
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DOI：
10.1089/apc.2005.19.853
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发表时间：
2005-12-01
影响因子：
4.9
通讯作者：
Yu, YH
中科院分区：
文献类型：
--
作者：
Chen, XS;Yin, YP;Yu, YH
对昆明市暗娼人群性传播感染现状进行了横断面调查。共有505名性工作者参与了调查。所有合格的参与者均签署了知情同意书。通过直接结构化访谈收集参与者的人口统计学、行为和临床信息。采集棉拭子检测沙眼衣原体、淋病奈瑟菌和阴道毛滴虫，采集血清标本检测HIV抗体，采用酶联免疫吸附试验（ELISA）筛查和Western blot确证，梅毒采用快速血浆反应素（RPR）检测，T.梅毒血凝（TPHA）确认，以及HSV-2抗体用HerpeSelect 2 ELISA。感染病原菌以沙眼衣原体（58.6%）、阴道毛滴虫（43.2%）和淋病奈瑟菌（37.8%）为主。327名（65.1%）性工作者有暴露于HSV-2感染的血清学证据。10%的人艾滋病毒感染呈阳性，都是注射吸毒者; 9.5%的人感染了梅毒。为性工作者及其顾客提供全面的预防和有效的性传播感染服务将是控制性传播感染，包括艾滋病毒的关键战略。性传播感染/艾滋病毒的政策和预防战略需要侧重于高风险亚群体，如性工作者（特别是注射毒品的性工作者）及其客户。
A cross-sectional prevalence survey of sexually transmitted infections (STIs) was conducted among female sex workers (FSWs) in Kunming, Yunnan Province, China. A total of 505 FSWs participated in the survey. All eligible participants gave informed consent. Demographic, behavioral, and clinical information of the participants was gathered by direct structured interviews. Tampon swabs were collected to test for Chlamydia trachomatis, Nesseria gonorrhoeae, and Trichomonas vaginalis and serum specimens were collected to test for HIV antibody by enzyme-linked immunosorbent assay (ELISA) screening and Western blot confirmation, syphilis with rapid plasma reagin (RPR) and T. pallidum hemagglutination (TPHA) confirmation, and for HSV-2 antibodies with the HerpeSelect 2 ELISA. The most prevalent bacterial STI was Chlamydia trachomatis (58.6%), followed by Trichomonas vaginalis (43.2%) and Neisseria gonorrhoeae (37.8%). Three hundred twenty-seven (65.1%) sex workers had serologic evidence of exposure to HSV-2 infection. Ten percent were positive for HIV infection, all injecting drug users (IDUs); and 9.5% had infection with syphilis. Comprehensive prevention and effective STI services for sex workers and their clients will be the key strategies to the control of STIs, including HIV. Policies and prevention strategies for STI/HIV need to focus on high-risk subpopulations, such as sex workers (particularly sex workers who inject drugs) and their clients.