Preservation and stability of cell therapy products: recommendations from an expert workshop.
Preservation and stability of cell therapy products: recommendations from an expert workshop.
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DOI：
10.2217/rme-2017-0073
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发表时间：
2017-07
影响因子：
2.7
通讯作者：
G. Stacey;C. Connon;K. Coopman;A. Dickson;B. Fuller;C. Hunt;P. Kemp;Julie E Kerby;Jennifer Man;P. Matejtschuk;H. Moore;John Morris;R. Oreffo;N. Slater;S. Ward;C. Wiggins;H. Zimmermann
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文献类型：
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作者：
G. Stacey;C. Connon;K. Coopman;A. Dickson;B. Fuller;C. Hunt;P. Kemp;Julie E Kerby;Jennifer Man;P. Matejtschuk;H. Moore;John Morris;R. Oreffo;N. Slater;S. Ward;C. Wiggins;H. Zimmermann
如果再生医学领域要提供治疗，需要快速扩展并在相当长的距离内向大量患者提供治疗。这将需要电池产品的有效稳定和运输。然而，生命科学家普遍对低温保存科学知之甚少，近几十年来，在细胞保存和储存技术方面只取得了有限的进展。将新的发展迅速转化为更广泛的细胞类型将是至关重要的，因为这将确保更深入地了解与成功保存和恢复细胞培养物相关的基本细胞生物学。本报告介绍了专家对这些问题和其他问题的共识，这些问题需要得到解决，以更有效地提供细胞疗法。
If the field of regenerative medicine is to deliver therapies, rapid expansion and delivery over considerable distances to large numbers of patients is needed. This will demand efficient stabilization and shipment of cell products. However, cryopreservation science is poorly understood by life-scientists in general and in recent decades only limited progress has been made in the technology of preservation and storage of cells. Rapid translation of new developments to a broader range of cell types will be vital, as will assuring a deeper knowledge of the fundamental cell biology relating to successful preservation and recovery of cell cultures. This report presents expert consensus on these and other issues which need to be addressed for more efficient delivery of cell therapies.