ASSOCIATION BETWEEN NUTRITIONAL-STATUS AND COGNITIVE-FUNCTIONING IN A HEALTHY ELDERLY POPULATION
ASSOCIATION BETWEEN NUTRITIONAL-STATUS AND COGNITIVE-FUNCTIONING IN A HEALTHY ELDERLY POPULATION
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DOI：
10.1001/jama.249.21.2917
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发表时间：
1983-01-01
影响因子：
120.7
通讯作者：
GARRY, PJ
中科院分区：
文献类型：
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作者：
GOODWIN, JS;GOODWIN, JM;GARRY, PJ
研究人员对 260 名 60 岁以上、没有已知身体疾病且未接受任何药物治疗的非住院男性和女性进行了营养状况与认知功能之间的关联评估。通过 3 天的食物记录以及特定营养素血液水平的生化测定来评估营养状况。认知状态通过 Halstead-Reitan 类别测试（抽象思维能力的非语言测试）和韦克斯勒记忆测试进行评估。血液中维生素 C 或 B12 水平较低的受试者在两项测试中得分较差。核黄素或叶酸水平较低的受试者在类别测试中得分较差。在控制了年龄、性别、收入水平和受教育程度后，这些差异仍然显着。亚临床营养不良可能在某些老年人可检测到的认知功能抑制中发挥很小的作用，或者认知功能抑制可能导致营养摄入减少。
The association between nutritional status and cognitive functioning was evaluated in 260 noninstitutionalized men and women older than 60 yr who had no known physical illnesses and were receiving no medications. Nutritional status was evaluated by 3-day food records and also by biochemical determination of blood levels of specific nutrients. Cognitive status was evaluated by the Halstead-Reitan Categories Test (a nonverbal test of abstract thinking ability) and by the Wechsler Memory Test. Subjects with low blood levels of vitamins C or B12 scored worse on both tests. Subjects with low levels of riboflavin or folic acid scored worse on the categories test. These differences remained significant after controlling for age, gender, level of income and amount of education. Subclinical malnutrition may play a small role in the depression of cognitive function detectable in some elderly individuals, or depressed cognitive function may result in reduced nutrient intake.