Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
Shear Force Fiber Spinning: Process Parameter and Polymer Solution Property Considerations
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DOI：
10.3390/polym11020294
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发表时间：
2019-02-01
期刊：
影响因子：
5
通讯作者：
Tang, Christina
中科院分区：
文献类型：
--
作者：
Dotivala, Arzan C.;Puthuveetil, Kavya P.;Tang, Christina
聚合物纳米纤维的应用（如用于研究细胞行为的传感器和支架），控制纤维的空间取向是很重要的。我们比较了使用剪切力纤维纺丝（即用旋转收集器接触一滴聚合物溶液以机械拉伸纤维）和静电纺丝在旋转滚筒上对纤维进行排列和图案的能力。以聚苯乙烯为模型体系，观察到剪切力纺丝比旋转滚筒纺丝的纤维间距更均匀，相对标准差分别为18%和39%。重要的是，这两种方法是互补的，使用旋转滚筒的静电纺丝获得的纤维间距类似于10微米，而使用剪切力纤维纺丝获得的纤维间距类似于250微米。为了扩展到更多的聚合物体系，我们使用聚合物缠结和毛细数。溶液性质有利于大毛细数（bbb50）防止液滴破裂，促进纤维形成。拉深比对于确定合适的工艺条件（流量，收集器的转速）以实现纤维的连续形成是有用的。这些考虑聚合物溶液性质和工艺参数的经验法则有望扩大该平台的使用，用于为细胞支架和其他应用创建多纤维层的分层结构。
For application of polymer nanofibers (e.g., sensors, and scaffolds to study cell behavior) it is important to control the spatial orientation of the fibers. We compare the ability to align and pattern fibers using shear force fiber spinning, i.e. contacting a drop of polymer solution with a rotating collector to mechanically draw a fiber, with electrospinning onto a rotating drum. Using polystyrene as a model system, we observe that the fiber spacing using shear force fiber spinning was more uniform than electrospinning with the rotating drum with relative standard deviations of 18% and 39%, respectively. Importantly, the approaches are complementary as the fiber spacing achieved using electrospinning with the rotating drum was similar to 10 microns while fiber spacing achieved using shear force fiber spinning was similar to 250 microns. To expand to additional polymer systems, we use polymer entanglement and capillary number. Solution properties that favor large capillary numbers (>50) prevent droplet breakup to facilitate fiber formation. Draw-down ratio was useful for determining appropriate process conditions (flow rate, rotational speed of the collector) to achieve continuous formation of fibers. These rules of thumb for considering the polymer solution properties and process parameters are expected to expand use of this platform for creating hierarchical structures of multiple fiber layers for cell scaffolds and additional applications.