MSTools-Web based application for visualization and presentation of HXMS data
MSTools-Web based application for visualization and presentation of HXMS data
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DOI：
10.1016/j.ijms.2010.07.030
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发表时间：
2011-04-30
影响因子：
1.8
通讯作者：
Man, Petr
中科院分区：
文献类型：
--
作者：
Kavan, Daniel;Man, Petr
氢/氘交换结合质谱是研究蛋白质结构变化和相互作用的一种优秀技术，特别是在传统的高分辨率结构技术不适用的情况下。这种技术的一个主要缺点是缺乏用于数据处理和结果可视化的通用软件工具。在这里，我们描述了一组PHP脚本，促进H/D数据可视化和表示。该应用程序在Web服务器上运行，可免费访问。它包括帮助准备H/D实验的工具，以及将HID交换数据的简单表格转换为HXMS社区使用的不同表示方式的工具。(C)2010 Elsevier B. V.保留所有权利。
Hydrogen/deuterium exchange coupled to mass spectrometry is an excellent technique to study protein structure changes and interactions, especially in cases where traditional high-resolution structural techniques are not applicable. A major drawback of this technique is the absence of universal software tools for data processing and visualization of the results. Here we describe a set of PHP scripts facilitating H/D data visualization and presentation. The application runs on a web server and is freely accessible. It comprises tools helping in preparation of H/D experiments as well as tools for turning simple tables with data on HID exchange into different ways of representation used by the HXMS community. (C) 2010 Elsevier B.V. All rights reserved.