Changes in Quadriceps Thickness and Echo Intensity in Chronic Stroke Survivors: A 3-Year Longitudinal Study
Changes in Quadriceps Thickness and Echo Intensity in Chronic Stroke Survivors: A 3-Year Longitudinal Study
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DOI：
10.1016/j.jstrokecerebrovasdis.2020.105543
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发表时间：
2021-03-01
影响因子：
2.5
通讯作者：
Moriyama, Hideki
中科院分区：
文献类型：
--
作者：
Akazawa, Naoki;Harada, Kazuhiro;Moriyama, Hideki
目的：本研究的目的是研究慢性卒中幸存者股四头肌肌肉质量和肌内脂肪组织的纵向变化。材料和方法：这项纵向研究包括34名居住在社区的慢性中风幸存者。最终，20名慢性中风幸存者接受了3年后的评估。14名慢性中风幸存者在随访中丢失。将3年随访和未随访的慢性卒中幸存者分别分为随访组和失访组。根据肌肉厚度和超声图像的回声强度，分别在基线和3年后评估股四头肌肌肉质量和肌肉内脂肪组织。结果：随访组与失访组在所有指标上均无显著差异。在随访组中，与基线相比，随访3年后，瘫痪侧(10.3%)和非瘫痪侧(17.0%)股四头肌厚度显著减少。3年后，与基线相比，患侧和非患侧股四头肌的回声强度明显增加(分别增加20.0%和24.9%)。偏瘫侧和非偏瘫侧的体重变化和股四头肌厚度变化之间存在显著的正相关关系。体重下降幅度较大的慢性卒中患者偏瘫和非偏瘫侧股四头肌厚度有较大幅度下降的趋势。结论：目前的结果表明慢性卒中幸存者的骨骼肌发生了显著的纵向变化。防止骨骼肌的继发性改变和限制体重的下降对于改善慢性中风幸存者的预后至关重要。
Objectives: The aim of the current study was to examine longitudinal changes in quadriceps muscle mass and intramuscular adipose tissue in chronic stroke survivors. Materials and Methods: In this longitudinal study included 34 chronic stroke survivors who lived in the community. Ultimately, 20 chronic stroke survivors received an after 3-year assessment. Fourteen chronic stroke survivors were lost at follow-up. Chronic stroke survivors who were followed and not followed during 3 years were categorized as follow-up group and lost follow-up group, respectively. The quadriceps muscle mass and intramuscular adipose tissue were assessed at baseline and after 3-year assessments based on muscle thickness and echo intensity in ultrasound images, respectively. Results: No significant differences in any characteristics were observed between the flow-up and lost follow-up groups. In the follow-up group, there was a significant decrease in quadriceps thickness on the paretic (10.3% decrease) and non-paretic (17.0% decrease) sides at follow-up after 3 years compared with baseline. There was a significant increase in quadriceps echo intensity on the paretic (20.0% increase) and non-paretic (24.9% increase) sides at follow-up after 3 years compared with baseline. There were significant positive relationships between changes in body weight and changes in quadriceps thickness on the paretic and non-paretic sides. Chronic stroke survivors with greater reductions in body weight showed a trend towards a greater decrease in quadriceps thickness on the paretic and non-paretic sides. Conclusions: The current results suggest marked longitudinal changes in the skeletal muscles in chronic stroke survivors. Preventing secondary changes in skeletal muscles and limiting decreases in body weight are essential for improving outcomes in chronic stroke survivors.