The genomic prehistory of the Indigenous peoples of Uruguay.
The genomic prehistory of the Indigenous peoples of Uruguay.
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DOI：
10.1093/pnasnexus/pgac047
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发表时间：
2022-05
期刊：
影响因子：
--
通讯作者：
Figueiro, Gonzalo
中科院分区：
文献类型：
--
作者：
Lindo, John;De La Rosa, Rosseirys;Santos, Andre L. C. D.;Sans, Monica;DeGiorgio, Michael;Figueiro, Gonzalo
乌拉圭人的史前史由于欧洲人的接触而变得非常复杂，就像大多数美洲人一样。在一系列军事行动消灭了游牧民族的最后残余之后，乌拉圭官方历史掩盖和稀释了前土著民族的多样性，变成了一个几乎灭绝的单一民族的叙述。在这里，我们介绍了欧洲人到来之前该地区土著人民的第一个全基因组序列，来自乌拉圭东部的一个考古遗址，可以追溯到2,000年前。我们发现了一个令人惊讶的联系，从巴拿马和巴西东部的古代人，但不是现代亚马逊人。这一结果可能表明了一条可能沿着大西洋海岸沿着迁移到南美洲的路线。我们还发现了一个以前在南美洲未被发现的独特祖先。虽然这项工作开始拼凑该地区的一些人口细微差别，但需要对乌拉圭各地的古代个体进行测序，以更好地了解欧洲人接触之前存在的古代史前史和遗传多样性，从而帮助重建现在乌拉圭的土著人口的历史。
The prehistory of the people of Uruguay is greatly complicated by the dramatic and severe effects of European contact, as with most of the Americas. After the series of military campaigns that exterminated the last remnants of nomadic peoples, Uruguayan official history masked and diluted the former Indigenous ethnic diversity into the narrative of a singular people that all but died out. Here, we present the first whole genome sequences of the Indigenous people of the region before the arrival of Europeans, from an archaeological site in eastern Uruguay that dates from 2,000 years before present. We find a surprising connection to ancient individuals from Panama and eastern Brazil, but not to modern Amazonians. This result may be indicative of a migration route into South America that may have occurred along the Atlantic coast. We also find a distinct ancestry previously undetected in South America. Though this work begins to piece together some of the demographic nuance of the region, the sequencing of ancient individuals from across Uruguay is needed to better understand the ancient prehistory and genetic diversity that existed before European contact, thereby helping to rebuild the history of the Indigenous population of what is now Uruguay.
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影响因子：
64.8
作者：
Mallick, Swapan;Li, Heng;Lipson, Mark;Mathieson, Iain;Gymrek, Melissa;Racimo, Fernando;Zhao, Mengyao;Chennagiri, Niru;Nordenfelt, Susanne;Tandon, Arti;Skoglund, Pontus;Lazaridis, Iosif;Sankararaman, Sriram;Fu, Qiaomei;Rohland, Nadin;Renaud, Gabriel;Erlich, Yaniv;Willems, Thomas;Gallo, Carla;Spence, Jeffrey P.;Song, Yun S.;Poletti, Giovanni;Balloux, Francois;van Driem, George;de Knijff, Peter;Romero, Irene Gallego;Jha, Aashish R.;Behar, Doron M.;Bravi, Claudio M.;Capelli, Cristian;Hervig, Tor;Moreno-Estrada, Andres;Posukh, Olga L.;Balanovska, Elena;Balanovsky, Oleg;Karachanak-Yankova, Sena;Sahakyan, Hovhannes;Toncheva, Draga;Yepiskoposyan, Levon;Tyler-Smith, Chris;Xue, Yali;Abdullah, M. Syafiq;Ruiz-Linares, Andres;Beall, Cynthia M.;Di Rienzo, Anna;Jeong, Choongwon;Starikovskaya, Elena B.;Metspalu, Ene;Parik, Juri;Villems, Richard;Henn, Brenna M.;Hodoglugil, Ugur;Mahley, Robert;Sajantila, Antti;Stamatoyannopoulos, George;Wee, Joseph T. S.;Khusainova, Rita;Khusnutdinova, Elza;Litvinov, Sergey;Ayodo, George;Comas, David;Hammer, Michael F.;Kivisild, Toomas;Klitz, William;Winkler, Cheryl A.;Labuda, Damian;Bamshad, Michael;Jorde, Lynn B.;Tishkoff, Sarah A.;Watkins, W. Scott;Metspalu, Mait;Dryomov, Stanislav;Sukernik, Rem;Singh, Lalji;Thangaraj, Kumarasamy;Paeaebo, Svante;Kelso, Janet;Patterson, Nick;Reich, David
通讯作者：
Reich, David
影响因子：
64.8
作者：
Moreno-Mayar, J. Victor;Potter, Ben A.;Willerslev, Eske
通讯作者：
Willerslev, Eske
影响因子：
3
作者：
Korneliussen TS;Albrechtsen A;Nielsen R
通讯作者：
Nielsen R
影响因子：
9.2
作者：
Chang CC;Chow CC;Tellier LC;Vattikuti S;Purcell SM;Lee JJ
通讯作者：
Lee JJ
影响因子：
56.9
作者：
Moreno-Mayar，J. Victor;Vinner，Lasse;Willerslev，Eske
通讯作者：
Willerslev，Eske