MECHANISM OF VISCOELASTIC DEFORMATION OF COLLAGENOUS TISSUE
MECHANISM OF VISCOELASTIC DEFORMATION OF COLLAGENOUS TISSUE
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DOI：
10.1038/247059a0
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发表时间：
1974-01-01
期刊：
影响因子：
64.8
通讯作者：
MCCRUM, NG
中科院分区：
文献类型：
--
作者：
COHEN, RE;HOOLEY, CJ;MCCRUM, NG
本文报道的实验目的是检验Rigbyet等人的惊人观察结果，即对于胶原组织，控制机械松弛的热激活过程在体温下突然改变。对于大鼠尾腱，证实了1在37° C以下，该过程是熵激活的：激活能ΔH=0。在37° C以上，Rigbyet等人得出结论，ΔHis很大，尽管他们的实验没有得到定量的结果。结果在两个方面是矛盾的。首先，熵激活虽然在概念上是可行的，但本质上是未知的。第二，速率过程在体温下会发生如此深刻的变化，这是否合理？我们现在已经解决了这两个悖论。
THE purpose of the experiment reported here was to examine the striking observation of Rigbyet al.1that for collagenous tissue the thermally activated process controlling mechanical relaxation changes abruptly at the body temperature. For rat tail tendon it was observed1that below 37° C the process is entropy activated: the activation energy ΔH=0. Above 37° C, Rigbyet al.1conclude that ΔHis large although their experiment does not yield a quantitative result. The result is paradoxical in two ways. First, entropy activation, although feasible conceptually, is essentially unknown in nature. Second, is it plausible that the rate process should change in such a profound way right at the body temperature? We have now resolved both paradoxes.