Chemical thermodynamics for growing systems
Chemical thermodynamics for growing systems
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DOI：
10.1103/physrevresearch.4.033191
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发表时间：
2022-01
影响因子：
4.2
通讯作者：
Yuki Sughiyama;A. Kamimura;Dimitri Loutchko;Tetsuya J. Kobayashi
中科院分区：
文献类型：
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作者：
Yuki Sughiyama;A. Kamimura;Dimitri Loutchko;Tetsuya J. Kobayashi
我们考虑增长的开放式化学反应系统（CRS），其中自催化化学反应被封装在一个有限的体积和它的大小可以改变与反应。生长CRS的热力学对于理解生物细胞和通过澄清其生长状态的物理条件和成本来设计原始细胞是不可或缺的。在这项工作中，我们建立了一个热力学理论的增长CRS通过扩展的海森几何结构的非增长CRS。该理论提供了环境条件，以确定不断增长的CRS的命运：增长，萎缩或平衡。我们还确定了热力学约束，一个限制可能的国家的不断增长的CRS和其他进一步限制区域的非平衡稳定增长状态可以存在。此外，我们估计的熵产生率在稳定的增长状态。非平衡态的增长源于热力学的可拓性，它不同于传统的定容非平衡态。这些结果是从一般热力学考虑导出的，而不假设任何特定的热力学势或反应动力学;即，它们仅仅基于热力学第二定律获得。
We consider growing open chemical reaction systems (CRSs), in which autocatalytic chemical reactions are encapsulated in a finite volume and its size can change in conjunction with the reactions. The thermodynamics of growing CRSs is indispensable for understanding biological cells and designing protocells by clarifying the physical conditions and costs for their growing states. In this work, we establish a thermodynamic theory of growing CRSs by extending the Hessian geometric structure of non-growing CRSs. The theory provides the environmental conditions to determine the fate of the growing CRSs; growth, shrinking or equilibration. We also identify thermodynamic constraints; one to restrict the possible states of the growing CRSs and the other to further limit the region where a nonequilibrium steady growing state can exist. Moreover, we evaluate the entropy production rate in the steady growing state. The growing nonequilibrium state has its origin in the extensivity of thermodynamics, which is different from the conventional nonequilibrium states with constant volume. These results are derived from general thermodynamic considerations without assuming any specific thermodynamic potentials or reaction kinetics; i.e., they are obtained based solely on the second law of thermodynamics.