The secretory cells of the submaxillary gland in the perinatal period of development in the rat
The secretory cells of the submaxillary gland in the perinatal period of development in the rat
复制标题
大鼠围生期发育期颌下腺分泌细胞
DOI：
10.1007/bf00337607
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
M. Dvořák
中科院分区：
文献类型：
--
作者：
M. Dvořák
电镜观察了胚胎19 ~ 22天和出生后1 ~ 6天大鼠颌下腺分泌细胞的分化情况。在此期间，发现了三种类型的分泌细胞，其主要区别在于其分泌颗粒的形态外观。除了前面描述的末端小管细胞和腺泡细胞外，我们还观察到具有多态颗粒的分泌细胞，其特征是在颗粒的基质中存在小的亲锇小体，无论是简单固定还是双重固定。这三种类型的分泌细胞在研究期间的时间顺序和数量表现变化。末小管细胞在胚胎第19天分化；胚胎第21天分泌细胞具有多形性颗粒；腺泡的腺细胞直到出生后才出现。假设末端小管的细胞是腺泡腺细胞的前体，而含有多形性颗粒的细胞代表它们之间的中间阶段。
Secretory cell differentiation in the submaxillary gland of the rat was investigated electron microscopically within the period of the 19th–22nd embryonic and the 1st–6th postnatal days.Within this period three types of secretory cells were identified which differed mainly in the morphological appearance of their secretory granules. In addition to the previously described cells of the terminal tubules and the glandular cells of the acini, we observed secretory cells with polymorphic granules, characterized by the presence of small osmiophilic bodies in the matrix of the granules, both after simple and double fixation. The chronological occurrence as well as the quantitative representation of these three types of secretory cells changes in the course of the period investigated. The cells of the terminal tubules are differentiated at the 19th embryonic day; the secretory cells with polymorphic granules by the 21st embryonic day; the glandular cells of the acini do not appear until after birth. It is presumed that the cells of the terminal tubules are precursors of the glandular cells of the acini and that the cells containing polymorphic granules represent an intermediate stage between them.