Dietary patterns and the incidence of type 2 diabetes
Dietary patterns and the incidence of type 2 diabetes
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DOI：
10.1093/aje/kwi039
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发表时间：
2005-02-01
影响因子：
5
通讯作者：
Reunanen, A
中科院分区：
文献类型：
--
作者：
Montonen, J;Knekt, P;Reunanen, A
在1967-1972年基线时无糖尿病的4，304名芬兰男性和女性中，研究了主要饮食模式预测2型糖尿病的能力。因子分析被用来确定饮食模式的饮食数据，收集使用1年的饮食史访谈。在23年的随访期间，共有383例2型糖尿病事件发生。确定了两种主要的饮食模式。标记为“谨慎”的模式的特点是水果和蔬菜的消费量较高，而标记为“保守”的模式的特点是黄油，土豆和全脂牛奶的消费量。谨慎模式和保守模式的模式评分的极端四分位数之间的相对风险（调整了非饮食混杂因素）分别为0.72（95%置信区间：0.53，0.97; p（趋势）= 0.03）和1.49（95%置信区间：1.11，2.00; p（趋势）= 0.01）。因此，谨慎饮食模式评分与2型糖尿病风险降低相关，保守模式评分与2型糖尿病风险增加相关。根据这些结果，似乎可以想象，通过改变饮食模式可以降低患2型糖尿病的风险。
Major dietary patterns were studied for the ability to predict type 2 diabetes mellitus in a cohort of 4,304 Finnish men and women aged 40-69 years and free of diabetes at baseline in 1967-1972. Factor analysis was used to identify dietary patterns from dietary data that were collected using a 1-year dietary history interview. A total of 383 incident cases of type 2 diabetes occurred during a 23-year follow-up. Two major dietary patterns were identified. The pattern labeled "prudent" was characterized by higher consumption of fruits and vegetables, and the pattern labeled "conservative" was characterized by consumption of butter, potatoes, and whole milk. The relative risks (adjusted for nondietary confounders) between the extreme quartiles of the pattern scores were 0.72 (95% confidence interval: 0.53, 0.97; p(trend) = 0.03) for the prudent pattern and 1.49 (95% confidence interval: 1.11, 2.00; p(trend) = 0.01) for the conservative pattern. Thus, the prudent dietary pattern score was associated with a reduced risk and the conservative pattern score was associated with an increased risk of type 2 diabetes. In light of these results, it appears conceivable that the risk of developing type 2 diabetes can be reduced by changing dietary patterns.