Heated proteins are still active in a functionalized nanoporous support.
Heated proteins are still active in a functionalized nanoporous support.
复制标题
加热的蛋白质在功能化纳米多孔载体中仍然具有活性。
DOI：
10.1002/smll.201202409
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Liu,Jun
中科院分区：
文献类型：
--
作者：
Chen,Baowei;Qi,Wen;Li,Xiaolin;Lei,Chenghong;Liu,Jun
即使在加热条件下，蛋白质几乎天然的构象和活性也可以通过非共价相互作用储存在功能化的纳米孔载体中。令人惊讶的是，从加热的蛋白质-纳米孔复合材料中释放出来的蛋白质可以保持其接近天然的构象和活性，而在相同的处理下，游离蛋白质会永久变性。
Even under heated conditions, the nearly native conformation and activity of a protein can be hoarded in a functionalized nanoporous support via non-covalent interaction. Surprisingly, the protein released from the heated protein-nanoporous composite can maintain its nearly native conformation and activity, while free proteins are permanently denatured under the same treatment.