The three modern faces of mercury.

The three modern faces of mercury.
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DOI:
10.1289/ehp.02110s111
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发表时间:
2002-02
影响因子:
10.4
通讯作者:
Clarkson TW
Clarkson TW
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Clarkson TW

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汞的三个现代“面孔”是我们对数十亿人接触鱼类中的甲基汞、汞合金牙齿填充物中的汞蒸气以及作为防腐剂添加到广泛使用的疫苗中的硫柳汞形式的乙基汞的风险的认识。在这篇文章中,我回顾了人类对这三种汞的暴露和毒理学。在可能的情况下讨论作用机制。从风险评估和行动机制的角度确定了我们目前知识中的主要差距。
The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam tooth fillings, and ethyl mercury in the form of thimerosal added as an antiseptic to widely used vaccines. In this article I review human exposure to and the toxicology of each of these three species of mercury. Mechanisms of action are discussed where possible. Key gaps in our current knowledge are identified from the points of view both of risk assessment and of mechanisms of action.
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