Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer
Cathepsin B, cathepsin H, cathepsin X and cystatin C in sera of patients with early-stage and inflammatory breast cancer
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DOI：
10.1177/172460080802300305
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发表时间：
2008-07-01
影响因子：
2
通讯作者：
Kos, J.
中科院分区：
文献类型：
--
作者：
Decock, J.;Obermajer, N.;Kos, J.
许多研究已将组织蛋白酶及其抑制剂半胱氨酸蛋白酶抑制剂 C 与肿瘤侵袭和转移联系起来。我们检查了是否可以在早期或炎性乳腺癌女性的血清中检测到组织蛋白酶 B、组织蛋白酶 H、组织蛋白酶 X 和胱抑素 C，以及它们是否与临床病理特征相关。术前血清取自 176 名早期乳腺癌患者（肿瘤大小
Numerous studies have linked cathepsins and their inhibitor cystatin C to tumor invasion and metastasis. We examined whether cathepsin B, cathepsin H, cathepsin X and cystatin C could be detected in sera from women with early-stage or inflammatory breast cancer and whether they correlated with clinicopathological characteristics. Preoperative serum was obtained from 176 patients with early-stage breast cancer (tumor size