Right ventricular wall motion abnormalities found in healthy subjects by cardiovascular magnetic resonance Imaging and characterized with a new segmental model

Right ventricular wall motion abnormalities found in healthy subjects by cardiovascular magnetic resonance Imaging and characterized with a new segmental model
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DOI:
10.1081/jcmr-120038528
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发表时间:
2004-01-01
影响因子:
6.4
通讯作者:
Trappe, HJ
Trappe, HJ
中科院分区:
医学2区
文献类型:
--
作者:
Sievers, B;Addo, M;Trappe, HJ

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瞄准使用一种新的右心室节段模型评价健康受试者的右心室壁运动异常。方法和结果。29名健康受试者(9名女性,20名男性,平均年龄48.9 ± 15岁)接受了心血管磁共振成像(CMR; 1.5-Tesla Sonata,Siemens,埃尔兰根,德国),以评价心脏功能和右心室壁运动。使用稳态自由旋进梯度回波序列(TrueFISP)。分析右室壁运动,并根据新的节段模型对运动障碍区域的位置进行分类。在29例受试者中的27例(93.1%)中观察到此类区域。运动障碍22例(75.9%),运动功能减退11例(37.9%),肿胀8例(27.6%)。横切面(86.2%)诊断的室壁运动异常数量显著高于短轴平面(13.8%)和水平纵切面(41.4%; p = 0.000)。结论右室壁运动异常是诊断致心肌病右室心肌病的标准之一。然而,我们的研究结果表明,它们也可以在健康受试者的调节带插入周围观察到,因此,在接受该疾病诊断检查的患者中,应谨慎解释其在该部位存在的意义。
Aim. To evaluate right ventricular wall motion abnormalities in healthy subjects using a new segmental model for the right ventricle. Methods and Results. 29 healthy subjects (9 female, 20 mate, mean age 48.9 +/- 15 years) underwent cardiovascular magnetic resonance imaging (CMR; 1.5-Tesla Sonata, Siemens, Erlangen, Germany) for the evaluation of cardiac function and right ventricular wall motion. A steady-state free precession gradient-echo sequence (TrueFISP) was used. Right ventricular wall motion was analyzed, and the site of areas of disordered motion was classified according to the new segmental model. Such areas were seen in 27 (93.1%) of the 29 subjects. Dyskinesia was found in 22 subjects (75.9%), hypokinesia in 11 (37.9%), and bulging in 8 (27.6%). The number of wall motion abnormalities diagnosed was significantly higher in the transverse plane (86.2%) than in the short-axis plane (13.8%) and the horizontal longitudinal plane (41.4%; p = 0.000). Conclusion. Right ventricular wall motion abnormalities are one of the criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. However, our findings indicate that they may also be seen around the insertion of the moderator band in healthy subjects, so that the significance of their presence at this site in patients undergoing diagnostic investigations for this disease should be interpreted with caution.